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Reported complications of dexmedetomidine were nausea/vomiting, bradycardiaĬonclusion: Dexmedetomidine can be used as a safe and efficient analgesic agent for Narcotics was significantly lower in the dexmedetomidine group. Ten studies found that the total consumption of Reported the significant lower incidence of acute pain after surgery inĭexmedetomidine group. Significant lower postoperative analgesia requirements and one study Most studies showed that pain score was significantly lower in theĭexmedetomidine group up to 24 hours after surgery. Results: From 1789 citations, 12 trials including 804 subjects met the inclusionĬriteria. Outcomes were postoperative pain intensity or incidence, postoperativeĪnalgesia duration, and the number of postoperative analgesic Methods: Medline, SCOPUS, Web of Science, and Cochrane databases were used to searchįor randomized controlled trials that investigated the analgesia effect ofĭexmedetomidine on post-thoracotomy/sternotomy pain in adults' patients. Objective: To review the effect of dexmedetomidine on acute post-thoracotomy/sternotomy Reached regarding the advantages of dexmedetomidine over the other However, no evidence-based conclusion has been The efficacy of dexmedetomidine as a single or as an adjuvant agent before,ĭuring and after surgery. Several randomized controlled trials have examined Introduction: Acute post-operative pain remains a troublesome complication ofĬardiothoracic surgeries. 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